Description

A-71915 (TFA) is a selective inhibitor of ANP receptor (atrial natriuretic peptide-receptor), induces apoptosis and decreases insulin secretion in RINm5F pancreatic β-cells[1].—Metabolism-protein/nucleotide metabolism–C71H117F3N26O17S2—-[1]Wong JC, et al. Pancreatic-β-cell survival and proliferation are promoted by protein kinase G type Iα and downstream regulation of AKT/FOXO1. Diab Vasc Dis Res. 2017 Sep;14(5):434-449.—-1727.98—-O=C([C@@H](N)CCCNC(N)=N)N[C@H](C(N[C@H](C(NCC(NCC(N[C@@H](C(C[C@@H](C(N[C@@H](C(N[C@@H](C(N[C@@H](C([N]1=CC2=C(C=C13)C=CC=C2)=O)[C@@H](CC)C)=O)CCCNC(N)=N)=O)CC(O)=O)=O)[C@@H](CC)C)=O)CCCNC(N)=N)=O)=O)=O)CC4CCCCC4)=O)CSSC[C@@H](NC([C@H](NC3=O)CCCNC(N)=N)=O)C(N)=O.OC(C(F)(F)F)=O–Metabolic Disease–10 mM in DMSO–Apoptosis—-Apoptosis–Peptides