Description

8-iso Prostaglandin F2α-d9 is the deuterium labeled 8-Isoprostaglandin F2α. 8-Isoprostaglandin F2α is an isoprostane produced by the non-enzymatic peroxidation of arachidonic acid in membrane phospholipids. 8-Isoprostaglandin F2α is present in human plasma in two distinct forms – esterified in phospholipids and as the free acid. 8-Isoprostaglandin F2α is a weak TP receptor agonist in vascular smooth muscle.–Applications–Formula-C20H25D9O5-Citation–References-[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. -CASNumber–MolecularWeight-363.54-Compound Purity–SMILES-O[C@@H]([C@@H]1C/C=CCCCC(O)=O)C[C@@H]([C@H]1/C=C/[C@H](CC([2H])(C([2H])(C([2H])(C([2H])([2H])[2H])[2H])[2H])[2H])O)O-Research_Area-Others-Solubility-10 mM in DMSO-Target-Endogenous Metabolite-Isoform–Pathway-Metabolic Enzyme/Protease-MCE Product type-Isotope-Labeled Compounds