Description

4-Succinimidyl-oxycarbonyl-α-(2-pyridyldithio)toluene is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].–Applications-Cancer-programmed cell death-Formula-C17H14N2O4S2-Citation–References-[1]Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16(5):315-337.-CASNumber-160854-54-6-MolecularWeight-374.43-Compound Purity–SMILES-O=C(ON1C(CCC1=O)=O)C2=CC=C(CSSC3=NC=CC=C3)C=C2-Research_Area-Cancer-Solubility-10 mM in DMSO-Target-ADC Linker-Isoform-Disulfide Cleavable Linker;Non-cleavable Linker-Pathway-Antibody-drug Conjugate/ADC Related-MCE Product type-ADC Related