Description

4-Pentynoyl-Val-Ala-PAB-PNP is a cleavable ADC linker, that has been used to synthesis cryptophycin conjugates[1]. 4-Pentynoyl-Val-Ala-PAB-PNP is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.–Applications-Cancer-programmed cell death-Formula-C27H30N4O8-Citation–References-[1]Cedric DESSIN, et al. Cryptophycin compounds and conjugates thereof. WO2022175222-CASNumber-1956294-76-0-MolecularWeight-538.55-Compound Purity–SMILES-C#CCCC(N[C@@H](C(C)C)C(N[C@@H](C)C(NC(C=C1)=CC=C1COC(OC2=CC=C(C=C2)[N+]([O-])=O)=O)=O)=O)=O-Research_Area-Others-Solubility-10 mM in DMSO-Target-ADC Linker-Isoform-Cleavable Linker-Pathway-Antibody-drug Conjugate/ADC Related-MCE Product type-ADC Related