Description

2-Hydroxyestrone-13C6 is the 13C-labeled 2-Hydroxyestrone. 2-Hydroxyestrone (Catecholestrone) is a specific receptor-mediated antiestrogenic agent. 2-Hydroxyestrone is anticarcinogenic[1][2].–Applications-Metabolism-protein/nucleotide metabolism-Formula-C12 13C6H22O3-Citation–References-[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. |[2]H L Bradlow, et al. 2-Hydroxyestrone: the ‘good’ estrogen. J Endocrinol. 1996 Sep;150 Suppl:S259-65.|[3]J Schneider, et al. Antiestrogen action of 2-Hydroxyestrone on MCF-7 human breast cancer cells. J Biol Chem. 1984 Apr 25;259(8):4840-5.|[4]M Nakagomi, et al. Quantitation of catechol estrogens and their N-acetylcysteine conjugates in urine of rats and hamsters. Chem Res Toxicol. 2000 Dec;13(12):1208-13.-CASNumber–MolecularWeight-292.32-Compound Purity–SMILES-[13CH3][13C@@]12[13C@]([13CH2][13CH2][13C]2=O)([H])[C@@]3([H])[C@@](CC1)([H])C4=CC(O)=C(O)C=C4CC3-Research_Area-Cancer; Endocrinology-Solubility-10 mM in DMSO-Target-Endogenous Metabolite;Estrogen Receptor/ERR;Isotope-Labeled Compounds-Isoform–Pathway-Metabolic Enzyme/Protease;Others;Vitamin D Related/Nuclear Receptor-MCE Product type-Isotope-Labeled Compounds