Description

17-AEP-GA, an HSP90 antagonist, is a potent inhibitor of glioblastoma cell proliferation, survival, migration and invasion. ADCs Toxin[1].–Applications-Cancer-programmed cell death-Formula-C34H50N4O8-Citation–References-[1]Katarzyna Miekus, et al. 17AEP-GA, an HSP90 antagonist, is a potent inhibitor of glioblastoma cell proliferation, survival, migration and invasion. Oncol Rep. 2012 Nov;28(5):1903-9.-CASNumber-75747-23-8-MolecularWeight-642.78-Compound Purity–SMILES-O=C(C(NCCN1CCCC1)=C2C[C@@H](C)C[C@H](OC)[C@H](O)[C@@H](C)/C=C(C)/[C@H](OC(N)=O)[C@@H](OC)/C=CC=C(C)C3=O)C=C(N3)C2=O-Research_Area-Cancer-Solubility-10 mM in DMSO-Target-ADC Cytotoxin;HSP-Isoform-HSP90;Traditional Cytotoxic Agents-Pathway-Antibody-drug Conjugate/ADC Related;Cell Cycle/DNA Damage;Metabolic Enzyme/Protease-MCE Product type-ADC Related