Description

10NH2-11F-Camptothecin is a Camptothecin (HY-16560) analogue that serves as an ADC cytotoxin for the synthesis of antibody-drug conjugates (ADCs). 10NH2-11F-Camptothecin can inhibit tumor growth and is used in cancer research[1].–Applications-Cancer-programmed cell death-Formula-C20H16FN3O4-Citation–References-[1]Petersen, M. E, et al. Camptothecin analogues, conjugates and methods of use. WO2022246576 A1.2022-01-12.-CASNumber-2873460-30-9-MolecularWeight-381.36-Compound Purity–SMILES-CC[C@@]1(C2=C(COC1=O)C(N3C(C(C(C3)=CC4=C5)=NC4=CC(F)=C5N)=C2)=O)O-Research_Area-Cancer-Solubility-10 mM in DMSO-Target-ADC Cytotoxin;Topoisomerase-Isoform–Pathway-Antibody-drug Conjugate/ADC Related;Cell Cycle/DNA Damage-MCE Product type-ADC Related