Description

α-Synuclein (61-95) (human) is the hydrophobic core region of α-synuclein, and induces neuronal cell death. α-Synuclein (61-95) (human) can be used for research of neurodegenerative diseases, including Alzheimer’s disease (AD) and Parkinson’s disease (PD)[1][2].—Neuroscience-Neurodegeneration–C141H235N39O49—-[1]Tabner BJ, et al. Formation of hydrogen peroxide and hydroxyl radicals from A(beta) and alpha-synuclein as a possible mechanism of cell death in Alzheimer’s disease and Parkinson’s disease. Free Radic Biol Med. 2002 Jun 1;32(11):1076-83.|[2]Emadi S, et al. Inhibiting aggregation of alpha-synuclein with human single chain antibody fragments. Biochemistry. 2004 Mar 16;43(10):2871-8.–154040-19-4–3260.61—-[C@H](CC1=CC=CC=C1)(C(N[C@@H](C(C)C)C(O)=O)=O)NC(CNC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC(CNC([C@@H](NC(CNC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC(CNC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC(CNC(CNC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@H](CCC(O)=O)N)=O)CCC(N)=O)=O)[C@H](C)C)=O)[C@@H](C)O)=O)CC(N)=O)=O)[C@H](C)C)=O)=O)=O)C)=O)[C@H](C)C)=O)C(C)C)=O)[C@@H](C)O)=O)=O)[C@H](C)C)=O)[C@@H](C)O)=O)C)=O)[C@H](C)C)=O)C)=O)CCC(N)=O)=O)CCCCN)=O)[C@@H](C)O)=O)C(C)C)=O)CCC(O)=O)=O)=O)C)=O)=O)CO)=O)[C@H](CC)C)=O)C)=O)C)=O)C)=O)[C@@H](C)O)=O)=O–Neurological Disease–10 mM in DMSO–α-synuclein—-Neuronal Signaling–Peptides