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Chemicals are an essential component of our daily lives, but some chemicals can severely damage our health or the environment. There is an increase in health problems that can be partially explained by the use of chemicals. Some man-made chemicals are found in the most remote places in the environment but also in our bodies. Chemicals are everywhere. In the EU, we have comprehensive chemicals legislation, spearheaded by REACH and CLP, which aims to ensure a high level of protection of human health and the environment. Specific groups of chemicals, such as biocides, pesticides, pharmaceuticals or cosmetics, are covered by their own legislation. In addition, the European Commission is addressing the challenges posed by endocrine disruptors, chemicals that interfere with the hormone system causing adverse health effects.