Description

Nε-(Carboxymethyl)-L-lysine (CML) is a unique post-translational modification (PTM) of proteins that is generated by the non-enzymatic glycation of lysine residues. Nε-(Carboxymethyl)-L-lysine is a relatively recently discovered modification, and has been found to be a major component of the advanced glycation endproducts (AGEs) found in multiple human diseases, such as diabetes, Alzheimer’s disease, and cancer[1].–Applications–Formula-C8H16N2O4-Citation–References-[1]Fu MX, et al. The advanced glycation end product, Nepsilon-(carboxymethyl)lysine, is a product of both lipid peroxidation and glycoxidation reactions. J Biol Chem. 1996 Apr 26;271(17):9982-6-CASNumber-5746-04-3-MolecularWeight-204.22-Compound Purity–SMILES-C(CCNCC(=O)O)C[C@@H](C(=O)O)N-Research_Area-Cancer; Metabolic Disease; Cardiovascular Disease-Solubility-10 mM in DMSO-Target-Biochemical Assay Reagents-Isoform–Pathway-Others-MCE Product type-Biochemical Assay Reagents