α-Conotoxin PnIA-Get quote

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α-Conotoxin PnIA, a potent and selective antagonist of the mammalian α7 nAChR, has the potential for the research of neurological conditions such as neuropathic pain and Alzheimer’s disease[1].—Neuroscience-Neurodegeneration–C65H95N19O22S4—-[1]Gene Hopping, et al. Hydrophobic Residues at Position 10 of α-conotoxin PnIA Influence Subtype Selectivity Between α7 and α3β2 Neuronal Nicotinic Acetylcholine Receptors. Biochem Pharmacol. 2014 Oct 15;91(4):534-42.–705300-84-1–1622.80—-O=C1[C@]2(N(C(=O)[C@H](CC(C)C)NC(=O)[C@H](CO)NC(=O)[C@]3(NC(=O)[C@@H](NC(CN)=O)CSSC[C@](NC(=O)[C@]4(N1CCC4)[H])(C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC(N)=O)C(=O)N5[C@](C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CC6=CC=C(O)C=C6)C(=O)N[C@H](C(N)=O)CSSC3)(CCC5)[H])[H])[H])CCC2)[H]–Neurological Disease–H2O–nAChR—-Membrane Transporter/Ion Channel;Neuronal Signaling–Peptides