Guanylin(human) (TFA)-1 mg

Description

Guanylin(human) TFA, a 15-amino acid peptide, is an endogenous intestinal guanylate cyclase activator. Guanylin(human) TFA is mainly found in gastrointestinal tract which regulates electrolytead water transport in intestinal and renal epithelia through cyclic GMP-dependent mechanism[1][2].–80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)–Metabolism-protein/nucleotide metabolism–C60H88F3N15O23S4—-[1]M G Currie, et al. Guanylin: an endogenous activator of intestinal guanylate cyclase. Proc Natl Acad Sci U S A. 1992 Feb 1;89(3):947-51.|[2]J Bełtowski. Guanylin and related peptides. J Physiol Pharmacol. 2001 Sep;52(3):351-75.—-1572.68—-O=C([C@@H](NC([C@@]1([H])NC([C@](NC([C@@H](NC([C@H](CSSC[C@](C(N[C@@](C(NCC(N[C@@H](CSSC1)C(O)=O)=O)=O)([H])[C@H](O)C)=O)([H])NC([C@@H](NC([C@@H](NC2=O)C)=O)C)=O)NC([C@H]([C@H](O)C)NC(CNC([C@@H]3CCCN3)=O)=O)=O)=O)CCC(O)=O)=O)([H])[C@@H](C)CC)=O)=O)C)N[C@H]2CC4=CC=C(C=C4)O.OC(C(F)(F)F)=O–Metabolic Disease–H2O–Endogenous Metabolite;Guanylate Cyclase—-GPCR/G Protein;Metabolic Enzyme/Protease–Peptides